Publications

A full list of publications is available via PubMed

Selected Primary Research Articles

Hubbard NW, Ames JM, Maurano M, Chu LH, Somfleth KY, Gokhale NS, Werner M, Snyder JM, Lichauco K, Savan R, Stetson DB, Oberst A. ADAR1 mutation causes ZBP1-dependent immunopathology. Nature 2022 607, 769–775 PMID: 35859177

 

Orozco SL, Daniels BP, Yatim N, Messmer MN, Quarato G, Chen H, Cullen S, Snyder AG, Jain P, Frase S, Tait SWG, Green DR, Albert M, Oberst A. RIPK3 activation leads to cyotokines synthesis that continues after loss of cell membrane integrity. Cell Reports 2019 Aug 27;28(9) PMID: 31461645

Snyder AG, Hubbard NW, Messmer MN, Kofman SG, Hagan CE, Orozco SL, Chiang K, Daniels BP, David Baker D, Oberst A. Intratumoral RIPK1/RIPK3 dependent necroptosis potentiates anti-tumor immunity. Science Immunology 2019 Jun 21;4(36) PMID: 31227597

Daniels BP, Kofman SB, Smith JR, Norris GT, Snyder AG, Kolb JP, Gao X, Locasale JW, Martinez J, Gale M Jr, Loo YM, Oberst A. (2019) The nucleotide sensor ZBP1 and kinase RIPK3 induce the enzyme IRG1 to promote an antiviral metabolic state in neurons. Immunity PMID: 30635240

Brault M, Olsen TM, Martinez J, Stetson DB, Oberst A. (2018) Intracellular nucleic acid sensing triggers necroptosis through synergistic type I IFN and TNF signaling. Journal of ImmunologyPMID: 29540580

Daniels BP, Snyder AG, Olsen TM, Orozco S, Oguin TH 3rd, Tait SWG, Martinez J, Gale M Jr, Loo YM, Oberst A. (2017) RIPK3 restricts viral pathogenesis via cell death-independent neuroinflammation. Cell. PMID: 28366204

Gutierrez, KD, Davis MA, Daniels BP, Olsen TM, Ralli-Jain P, Tait SWG, Gale Jr. M, Oberst A. (2017) MLKL activation triggers NLRP3-mediated processing and release of IL-1β independently of Gasdermin-DJournal of Immunology. PMID: 28130493

Yatim N, Jusforgues-Saklani H, Orozco S, Schulz O, Barreira da Silva R, Reis e Sousa C, Green DR, Oberst A, Albert ML. (2015) RIPK1 and NF-κB signaling in dying cells determines cross-priming of CD8⁺ T cells. Science. PMID: 26405229

Orozco S, Yatim N, Werner MR, Tran H, Gunja SY, Tait SWG, Albert ML, Green DR, Oberst A. (2014) RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosisCell Death and Differentiation. PMID: 24902904

Selected Reviews and Commentaries

Snyder AG, Oberst A. The Antisocial Network Annu. Rev. Immunol. 2021 PMID: 33441019

 

Krummel M, Blish C, Kuhns M, Cadwell K, Oberst A, Goldrath A, Ansel KM, Chi H, O'Connell R, Wherry EJ, Pepper M; Future Immunology Consortium. Universal Principled Review: A Community-Driven Method to Improve Peer Review Cell. 2019 Dec 12;179(7):1441-1445.PMID: 31835023

Messmer MN, Snyder AG, Oberst A. (2018) Comparing the effects of different cell death programs in tumor progression and immunotherapyCell Death and Differentiation. PMID: 30341424

Orozco S, Oberst A. (2017) RIPK3 in cell death and inflammation: The good, the bad, and the ugly. Immunological Reviews. PMID: 28462521

Brault M, Oberst A. (2016) Controlled detonation: evolution of necroptosis in pathogen defense. Immunology & Cell Biology. PMID: 27909314

Oberst A. (2016) Death in the fast lane: What's next for necroptosis? The FEBS Journal. PMID: 26395133